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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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Pyrithione is an inhibitor of membrane transport processes in fungi and acts as a potent antibiotic aspergillic acid. When Penicillium mycelia are incubated with Pyrithione, a significant decrease in the activities of various independently regulated transport systems is observed.
Inhibits membrane transport processes in fungi.
Functions as a potent antibiotic aspergillic acid.
Decreases activities of various independently regulated transport systems.
Inhibits 35SO42- transport in P. notatum in vitro (IC50 = 0.6 mM).
Inhibits L-[14C]-phenylalanine transport in P. chrysogenum in vitro (IC50 = 0.6 mM).
Reduces ATP levels in P. chrysogenum to about 40% of initial level at 2.5 mM.
Prevents incorporation of internal accumulated L-[14C]tryptophan and 35SO42- into protein at 5 mM.
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1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine is a thymidine analog with a purity of 99.68% and a molecular weight of 242.23. This compound exhibits insertional activity towards replicated DNA, making it suitable for labeling cells and tracking DNA synthesis. It also demonstrates antiviral activity against HBV in human 2.2.15 cells with an EC50 of 10 μg/mL and against DHBV in duck hepatocytes with an EC50 of 4.13 μM. Cytotoxicity against human HuH7 cells is observed with a CC50 of > 200 μg/mL.
Thymidine analog
Exhibits insertional activity towards replicated DNA
Used for labeling cells and tracking DNA synthesis
Demonstrates antiviral activity against HBV and DHBV
High purity of 99.68%
Appears as a white to off-white solid
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TyraMax Dyes are next-generation tyramide (TSA) dyes for spatial biology with colors from blue to near-IR named for their excitation/emission They are stable in amplification buffer with advantages in color selection brightness and photostability versus other TSA dyes 100X in DMSO 100 uL
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